t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate - Names and Identifiers
Name | 2-Methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate
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Synonyms | 1-boc-pyrrole-3-boronic acid, pinacol ester 1-BOC-Pyrrole-3-boronic acid, pinacol ester 2-Methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborola... N-BOC-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole ert-butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole-1-carboxylate tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole-1-carboxylate t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate Tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate 2-Methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate 1H-Pyrrole-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester
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CAS | 935278-73-2
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InChI | InChI=1S/C15H24BNO4/c1-13(2,3)19-12(18)17-9-8-11(10-17)16-20-14(4,5)15(6,7)21-16/h8-10H,1-7H3 |
t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate - Physico-chemical Properties
Molecular Formula | C15H24BNO4
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Molar Mass | 293.17 |
Density | 1.04±0.1 g/cm3(Predicted) |
Melting Point | 76-77 °C |
Boling Point | 381.3±34.0 °C(Predicted) |
pKa | -6.09±0.70(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate - Introduction
1-BOC-pyrrole-3-boronic acid, pinacol ester is an organic compound with the chemical name 2-Methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate.
The properties of the compound are as follows:
-Appearance: White solid or oily liquid.
-Molecular formula: C14H23BN2O4.
-Molecular weight: 296.16g/mol.
-Melting point: about 70-75°C.
-Boiling point: about 324°C.
1-BOC-pyrrole-3-boronic acid, pinacol ester has the following uses:
-Organic synthesis is often used as a condensation reagent or reagent intermediates.
-can be used to prepare compounds with biological activity, such as drugs, pesticides, etc.
1-BOC-pyrrole-3-boronic acid, pinacol ester is prepared as follows:
First, pyrrole is condensed with 4,4, 5,5-tetramethyl -1,3, 2-dioxaboropropionyl acetate to obtain an intermediate, and then the intermediate is esterified with 2-methyl-2-propanol to generate the final product.
Some safety information to note when using and handling 1-BOC-pyrrole-3-boronic acid, pinacol ester:
-This compound may be irritating to the eyes, skin and respiratory system, please avoid contact.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, when performing operations.
-It should be stored in a closed container, away from high temperature and fire sources.
-During storage, please avoid contact with oxidants, acids and other substances to prevent fire or explosion.
-Before use, please carefully read and follow the relevant safety guidelines and operating procedures.
Last Update:2024-04-09 21:01:54